Student dies from highly dangerous incurable virus

A student died from brain swelling fever caused by a virus on the World Health Organization‘s watch list.

The 24-year-old student is the second person to die from Nipah infection in the same town in southern India in three months, following the death of a 14-year-old kid in July.

According to officials, 151 persons who had contact with the student victim are now being watched to ensure they do not exhibit symptoms in order to stop the spread.

There is no vaccination to prevent Nipah, and no medicine to cure it, so patients are provided supportive care but must eventually fight the infection on their own.

Its fatality rate is estimated at between 40% and 70% of patients, and around 20% of those who survive are left with ongoing neurological problems such as seizures or personality changes.

Although some people show no symptoms at all once infected, others develop fever and muscle pain, and in severe cases brain swelling, which can progress to a coma in 24 to 28 hours.

The virus was only discovered in 1999, in Malaysia, and is mainly spread from pigs or fruit bats to people, or from contaminated food, although human-to-human transmission can also happen.

The student who died this month, who had come from Bengaluru, started showing symptoms on September 4 and died five days later, said R. Renuka, a district medical officer in the town of Malappuram, located in the north of the state of Kerala.

A blood sample sent to the National Institute of Virology in Pune confirmed a Nipah infection on September 9, Renuka said.

Five other people who have developed primary symptoms have had blood samples drawn and they were sent for tests, she said, without saying if they were primary contacts of the dead person.

Symptoms of Nipah virus

Human infections range from asymptomatic to acute respiratory infection (mild, severe), and fatal encephalitis. Initial symptoms include:

• Fever
• Headaches
• Myalgia (muscle pain)
• Vomiting
• Sore throat

This can be followed by:

• Dizziness
• Drowsiness
• Altered consciousness
• Brain swelling
• Seizures
• Coma

Some people can also experience atypical pneumonia and severe breathing problems, including acute respiratory distress.

The incubation period (time from infection to when symptoms start) is believed to range generally from 4 to 14 days.Approximately 20% of patients are left with residual neurological consequences such as seizure disorder and personality changes. The case fatality rate is estimated at 40% to 75%, which can vary by outbreak depending on local capabilities.

Nipah has been linked to the deaths of dozens of people in Kerala since its first appearance in the state in 2018.

Parts of the state are among those most at risk globally for outbreaks of the virus.

Nipah is classified as a priority pathogen by the World Health Organization because of its potential to trigger an epidemic and because we do not yet have a vaccine or a cure.

Other viruses on the epidemic priority list include Ebola, Marburg, Lassa Fever, Zika and SARS. They are listed urgently needing more research and development to try and find effective ways to respond to them.

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